オオモト　マサノリ
  大本　まさのり
   所属   薬学部 薬学科
   職種   教授
言語種別 英語
発行・発表の年月 2020/03
形態種別 学術論文
査読 査読あり
標題 Protective Effects of Butein on Corticosterone-induced Cytotoxicity in Neuro2A Cells
執筆形態 共著
掲載誌名 IBRO Reports
掲載区分国外
出版社・発行元 Elsevier
著者・共著者 Masanori Ohmoto, Yukina Shibuya, Shihori Taniguchi, Tomoki Nakade, Masaaki Nomura, Yuri Ikeda-Matsuo, and Tohru Daikoku.
概要 We examined the protective effect of butein on corticosterone (CORT)-induced cytotoxicity and neurite growth during cell differentiation of mouse neuroblastoma Neuro2A (N2A) cells. Moreover, the effect on cultured cells by high concentrations of butein was confirmed. This study suggests that low concentration of butein can prevent CORT-induced cytotoxicity in N2A cells, and provides preliminary results supporting some of the beneficial roles of butein in neuroprotection.