オヤマダ マサヒト
Oyamada Masahito
小山田 正人 所属 藤女子大学 人間生活学部 食物栄養学科 職種 特任教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2013 |
形態種別 | 研究論文(学術雑誌) |
査読 | 査読あり |
標題 | Connexin expression and gap-junctional intercellular communication in ES cells and iPS cells |
執筆形態 | 共著 |
掲載誌名 | FRONTIERS IN PHARMACOLOGY |
掲載区分 | 国外 |
出版社・発行元 | FRONTIERS RESEARCH FOUNDATION |
巻・号・頁 | 4 |
担当区分 | 筆頭著者 |
著者・共著者 | Masahito Oyamada,Kumiko Takebe,Aya Endo,Sachiko Hara,Yumiko Oyamada |
概要 | Pluripotent stem cells,i.e., embryonic stem (ES) and induced pluripotent stem (iPS) cells, can indefinitely proliferate without commitment and differentiate into all cell lineages. Many studies have demonstrated that mouse and human iPS cells are highly similar but not identical to their respective ES cell counterparts. The potential to generate basically any differentiated cell types from these cells offers the possibility to establish new models of mammalian development and to create new sources of cells for regenerative medicine. ES cells and iPS cells also provide useful models to study connexin expression and gap-junctional intercellular communication (GJIC) during cell differentiation and reprogramming. Because a substantial number of papers on these subjects have been published since our report, this Mini Review summarizes currently available data on connexin expression and GJIC in ES cells and iPS cells during undifferentiated |
DOI | 10.3389/fphar.2013.00085 |
ISSN | 16639812 |
PermalinkURL | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84881576252&origin=inward |