オヤマダ マサヒト
Oyamada Masahito
小山田 正人 所属 藤女子大学 人間生活学部 食物栄養学科 職種 特任教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2006 |
形態種別 | 研究論文(学術雑誌) |
査読 | 査読あり |
標題 | Different changes in the expression of multiple kinds of tight-junction proteins during ischemia-reperfusion injury of the rat ileum |
執筆形態 | 共著 |
掲載誌名 | ACTA HISTOCHEMICA ET CYTOCHEMICA |
出版社・発行元 | JAPAN SOC HISTOCHEMISTRY&CYTOCHEMISTRY |
巻・号・頁 | 39(2),pp.35-45 |
著者・共著者 | Kaori Inoue,Masahito Oyamada,Shoji Mitsufuji,Takeshi Okanoue,Tetsuro Takamatsu |
概要 | Dysfunction of tight junctions ( TJs), located at the most apical part of the intestinal epithelium, is believed to result in various complications in intestinal disease. However, the behaviors of multiple kinds of TJ proteins during ischemia-reperfusion injury are not understood in detail. To determine changes in expression and localization of TJ proteins during intestinal-barrier recovery, we induced intestinal ischemia-reperfusion injury in rats, measured mucosa-to-blood permeability of fluorescein isothiocyanate-dextran-4 kDa, and compared it with spatiotemporal changes of ZO-1, occludin, and claudin-1, -2, -3, -4, and -5 by immunoconfocal microscopy. |
DOI | 10.1267/ahc.05048 |
ISSN | 00445991 |
PermalinkURL | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33646269016&origin=inward |