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オヤマダ マサヒト
Oyamada Masahito
小山田 正人 所属 藤女子大学 人間生活学部 食物栄養学科 職種 特任教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 1986/01 |
| 形態種別 | 研究論文（学術雑誌） |
| 標題 | Induction of a novel Ca2+-dependent chymotrypsin-like serine protease by tumor promoters in rat livers |
| 執筆形態 | 共著 |
| 掲載誌名 | Journal of the National Cancer Institute |
| 巻・号・頁 | 77,pp.121-125 |
| 著者・共著者 | Aiko Kaneko,Katsuhiko Enomoto,Masahito Oyamada,Norimasa Sawada,Kimimaro Dempo,Michio Mori |
| 概要 | Induction of a microsomal Ca2+-dependent serine protease by hepatic tumor promoters was studied. Male F344 rats were fed a diet containing one of the following promoting agents: phenobarbital (CAS: 50-06-6), dichlorophenyltrichloroethane (CAS: 50-29-3), butylated hydroxytoluene, ethyl-α-chlorophenoxyisobutyrate (CAS: 128-95-0), or 17-α-ethynylestradiol (CAS: 57-63-6) or a nonpromoting agent, diphenylhydantoin (CAS: 57-41-0), for 1 week. By treatment with promoters, the protease activity in the microsomal fraction was increased to threefold to fivefold that of control, whereas only a slight increase of activity was found after diphenylhydantoin treatment. |
| DOI | 10.1093/jnci/77.1.121 |
| ISSN | 00278874 |
| PMID | 3522996 |
| PermalinkURL | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022555825&origin=inward |