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ヒルタ オサム
Osamu HIRUTA
蛭田 修 所属 熊本保健科学大学 品質保証・精度管理学共同研究講座 熊本保健科学大学大学院 保健科学研究科 保健科学専攻 職位 特命教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 1996/04 |
| 形態種別 | 研究論文 |
| 査読 | 査読あり |
| 標題 | Optimization and Scale-Up of γ-Linolenic Acid Production by Mortierella ramanniana MM 15-1,a High γ-Linolenic Acid Producing Mutant |
| 執筆形態 | 共著 |
| 掲載誌名 | Journal of fermentation and bioengineering |
| 掲載区分 | 国内 |
| 巻・号・頁 | 82(4),pp.366-370 |
| 著者・共著者 | Osamu Hiruta, Takafumi Futamura, Hidehi Takebe, Atsuyuki Satoh, Yasushi Kamisaka, Toshihiro Yokochi, Toro Nakahara, Osamu Suzuki |
| 概要 | Optimum conditions for cultivation of Mortierella ramanniana mutant MM 15-1 were investigated with an aim of producing a lipid which contains high γ-linolenic acid (GLA). Although both pellet and filamentous forms of this mutant were observed during the cultivation, the pellets accumulated lipid with higher GLA content than the filamentous forms. The effects of culture conditions on pellet formation were therefore investigated in a 30-l jar fermentor. Furthermore, when this process was scaled up to a 10-kl fermentor, using the impeller tip velocity as the scale-up parameter, both the pellet formation and the lipid production as well as the GLA content of the lipid were consistent with those obtained in the 30-l jar fermentor. |