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ヨコヤマ トシロウ
TOSHIRO YOKOYAMA
横山 俊朗 所属 熊本保健科学大学 保健科学部 医学検査学科 職位 教授 |
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| 言語種別 | 日本語 |
| 発行・発表の年月 | 2005 |
| 形態種別 | 研究論文（学術雑誌） |
| 査読 | 査読あり |
| 標題 | Image analysis of irregularity of cluster shape in cytological diagnosis of breast tumors:cluster analysis with 2D-fractal dimension. |
| 執筆形態 | 共著 |
| 掲載誌名 | Diagn Cytopathol. Aug; |
| 掲載区分 | 国内 |
| 巻・号・頁 | 33(2),71-77頁 |
| 著者・共著者 | Toshiro Yokoyama（主著）, Akihiko Kawahara, Masayoshi Kage. |
| 概要 | "We evaluated the irregularity in cell cluster shape using fractal dimension analysis, and determined the correlation to cluster size. The irregularity in the IDC cluster shape was higher than that in the FA cluster shape. However, six cases (28.5%) of 21 FA clusters showed high fractal dimensions similar to those for IDC. The clusters were classified by cluster analysis into three types: IDC clusters, FA with irregular cluster shape, and FA with no irregular clusters. The average cell cluster area of the FA with irregular shape was found to be about three times larger than that of IDC clusters. When the differential diagnosis between IDC and FA is difficult, it is important to focus on irregularities in the shape and on overall size of the cell clusters. For accurate diagnosis, the cell cluster shape is as important as the individual cellular atypia. |