ヨコヤマ トシロウ   TOSHIRO YOKOYAMA
  横山 俊朗
   所属   熊本保健科学大学  保健科学部 医学検査学科
   職位   教授
言語種別 日本語
発行・発表の年月 2012
形態種別 研究論文(学術雑誌)
査読 査読あり
標題 Transient reduction and activation of circulating dendritic cells in patients with acute myocardial infarction.
執筆形態 共著
掲載区分国内
出版社・発行元 Int J Cardiol in press
著者・共著者 Daisuke Fukui , Hideo Yasukawa, Yusuke Sugi, Toyoharu Oba, Takanobu Nagata, Sachiko Kyogoku, Nobuyoshi Futamata, Toshiro Yokoyama, Shinji Yokoyama, Hisashi Kai, Takafumi Ueno, Masayoshi Kage, Tsutomu Imaizumi
概要 Dendritic cells (DCs) are highly potent professional antigen-presenting cells that play a central role in initiating the primary immune response. Accumulating evidence suggests that immune-mediated inflammation plays an important role in the pathophysiology of AMI, but the mechanism that triggers such immune responses is unknown.Our findings suggest that the transient reduction and activation of circulating DCs may play important roles in the pathophysiology of myocardial injury after AMI.