アオキ ユウジ
Yuji.AOKI
青木 雄次
- 所属 松本大学大学院 健康科学研究科 健康科学専攻
- 松本大学 人間健康学部 健康栄養学科
- 職種 教授
| 言語種別 | 英語 |
| 発行・発表の年月 | 2023/09 |
| 形態種別 | 総説・解説（学術雑誌） |
| 査読 | 査読あり |
| 標題 | Associations of dietary methyl-group donors with epigenetics through one-carbon metabolism in breast cancer risk |
| 執筆形態 | 共著 |
| 掲載誌名 | Acta Scientific Nutritional Health |
| 掲載区分 | 国外 |
| 出版社・発行元 | Acta Scientific |
| 巻・号・頁 | 7(9),pp.91-95 |
| 総ページ数 | 5 |
| 担当区分 | 責任著者 |
| 著者・共著者 | Risa Asada, Sho Maruyama, Gakuto Homma and Yuji Aoki |
| 概要 | In this mini-review, we provide a brief overview of epigenetic modifications, particularly in relation to one-carbon metabolism, and explore the potential impact of dietary methyl-group donor intake on breast cancer risk. Overall, the influence of dietary intake of folate or methionine on breast cancer risk may exhibit a potential U-shaped relationship. However, the exact contribution of methyl-group donors through epigenetics to breast cancer development remains somewhat illusive. The metabolic network involved in one-carbon metabolism suggests that high folate or methionine intake may contribute to breast cancer progression. As breast cancer incidence continues to rise among Asian women, further research on the interactions between nutrition and epigenetics, which may be reversible, is expected to advance breast cancer prevention and treatment. |