エバラ サトミ   EBARA SATOMI
  榎原 智美
   所属   看護学部 看護学科
   職種   准教授
言語種別 英語
発行・発表の年月 2023/08/06
形態種別 研究論文(学術雑誌)
標題 Structure and barrier functions of the perineurium and its relationship with
associated sensory corpuscles: A review
執筆形態 共著
掲載誌名 Biomedical Research (Tokyo)
掲載区分国外
巻・号・頁 43(5),pp.145-159
総ページ数 14
担当区分 最終著者
著者・共著者 Toshihiko IWANAGA, Hiromi TAKAHASHI-IWANAGA, Junko NIO-KOBAYASHI, Satomi EBARA
概要 Peripheral nerves are provided with a blood-nerve barrier which prevents the invasion of harmful substances and pathogens, and also regulates metabolic and ionic homeostasis within nerve fasci-cles. The barrier functions are attributed to both the concentric layer of flattened cells in the peri-neurium and blood vessels running in the endoneurium. The perineurial cells develop continuous tight junctions as a diffusion barrier. To identify the cellular origins of the nerve sheath, marker proteins such as glial specific S100 protein, GLUT1, endoneurial CD34, and EMA (epithelial membrane antigen) are useful. Immunohistochemical findings for these markers are reviewed in this paper, focusing on the perineurium and endoneurium and their derivatives, Pacinian and Meissner corpuscles.
researchmap用URL https://www.jstage.jst.go.jp/article/biomedres/43/5/43_145/_article/-char/ja