エバラ サトミ
EBARA SATOMI
榎原 智美 所属 看護学部 看護学科 職種 准教授 |
|
言語種別 | 英語 |
発行・発表の年月 | 2023/08/06 |
形態種別 | 研究論文(学術雑誌) |
標題 | Structure and barrier functions of the perineurium and its relationship with
associated sensory corpuscles: A review |
執筆形態 | 共著 |
掲載誌名 | Biomedical Research (Tokyo) |
掲載区分 | 国外 |
巻・号・頁 | 43(5),pp.145-159 |
総ページ数 | 14 |
担当区分 | 最終著者 |
著者・共著者 | Toshihiko IWANAGA, Hiromi TAKAHASHI-IWANAGA, Junko NIO-KOBAYASHI, Satomi EBARA |
概要 | Peripheral nerves are provided with a blood-nerve barrier which prevents the invasion of harmful substances and pathogens, and also regulates metabolic and ionic homeostasis within nerve fasci-cles. The barrier functions are attributed to both the concentric layer of flattened cells in the peri-neurium and blood vessels running in the endoneurium. The perineurial cells develop continuous tight junctions as a diffusion barrier. To identify the cellular origins of the nerve sheath, marker proteins such as glial specific S100 protein, GLUT1, endoneurial CD34, and EMA (epithelial membrane antigen) are useful. Immunohistochemical findings for these markers are reviewed in this paper, focusing on the perineurium and endoneurium and their derivatives, Pacinian and Meissner corpuscles. |
researchmap用URL | https://www.jstage.jst.go.jp/article/biomedres/43/5/43_145/_article/-char/ja |