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タグチ レイナ
TAGUCHI REINA
田口 玲奈 所属 鍼灸学部 鍼灸学科 職種 准教授 |
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| 言語種別 | 日本語 |
| 発行・発表の年月 | 2003 |
| 形態種別 | 研究論文 |
| 標題 | Differences of electroacupunc-ture-induced analgesic effect in normal and inflammatory condi-tions in rats.2 Differences of electroacupunc-ture-induced analgesic effect in normal and inflammatory condi-tions in rats. |
| 執筆形態 | 共著 |
| 掲載誌名 | Am. J. Chin. Med. |
| 巻・号・頁 | 31(6),955-965頁 |
| 担当範囲 | 本研究の施行から論文作成まで全てを担当した。 |
| 著者・共著者 | Sekido R 、Ishimaru K、Masakazu S |
| 概要 | The aim of the present study was to compare (1) the individual variation of EAA, (2) the durability of EAA and (3) the effect of naloxone on EAA between normal rats and rats subjected to acute inflammatory pain. EA. EAA was elicited in 15 of 29 normal rats. EAA in the responder group was almost com-pletely antagonized by i.p. injection of naloxone. In contrast, in all the rats with car-rageenan-induced inflammation, EAA was elicited, lasted for at least 24 h after car-rageenan injection, and was dose-dependently antagonized by i.pl. injection, but not by i.p. injection of naloxone. It seems likely that the EAA in the rats with carrageenan-induced in-flammation differs from that in normal rats, and these findings suggest that peripheral opioid receptors are involved in EAA during inflammatory conditions. |